The Arctic Liquid Freezer III 280 and the Arctic Liquid Freezer III 420 represent a tie in this objective comparison, as each component secures two spec wins. The primary advantage for the 280 model is its MSRP, which is 14% better than its counterpart. Conversely, the 420 model offers a significant physical advantage, featuring a radiator size that is 50% larger than the 280 version.

Choose the Arctic Liquid Freezer III 280 if you prioritize a lower MSRP and need a more compact cooling solution for your build. Select the Arctic Liquid Freezer III 420 if your primary requirement is the increased radiator size, which provides a 50% advantage in surface area. Both coolers offer balanced specifications, so your final decision should depend on whether you value the cost efficiency of the smaller unit or the physical capacity of the larger one.