The NVIDIA RTX 4080 is the objective winner of this comparison, securing victories in ten out of fourteen measured specifications. Its most significant advantage over the competition is its shader unit count, which is 217% higher. This substantial lead in core architecture ensures that the NVIDIA RTX 4080 provides superior raw processing power compared to the NVIDIA RTX 5060 Mobile, which only outperformed its counterpart in three specific categories.

Users prioritizing maximum performance should select the NVIDIA RTX 4080 for its vastly superior shader unit capacity. Conversely, the NVIDIA RTX 5060 Mobile is the logical choice for budget-conscious buyers, as it offers a 100% advantage in MSRP. Choosing between these two components depends entirely on whether your primary requirement is the high-end computational throughput provided by the former or the cost-efficiency offered by the latter.