The ASUS ROG STRIX X870E-I GAMING WIFI is the objective winner of this comparison, securing a lead in seven of the fourteen evaluated specifications. Its most significant advantage is the USB Type-C connectivity, which offers a 200% improvement over the alternative. This superior interface capability makes it the more advanced option for users prioritizing modern peripheral connectivity and high-speed data transfer standards within their system build.

Choose the ASUS ROG STRIX X870E-I GAMING WIFI if your primary requirement is advanced USB Type-C support for modern devices. Conversely, select the MSI PRO B660M-A WIFI DDR4 if your build necessitates a higher volume of storage drives, as it provides a 100% advantage in available SATA ports. Your decision should depend on whether you prioritize cutting-edge external connectivity or the ability to connect a greater number of internal storage components.